Description
[ CAS No. ] 84371-65-3
[ Molecular Formula ] C29H35NO2
[ Molecular Weight ] 429.5937
[ Purity ] ≥98.5%
[ Appearance ] faint yellow powder
[ Density ] 1.18 g/cm3
[ Boiling Point ] 628.6 °C at 760 mmHg
[ Melting Point ] 195-198°C
[ Flash Point ] 334 °C
[ Solubility ] Soluble to 100 mM in DMSO and to 50 mM in Ethanol
[ Biological Activity ]
Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro and in vivo . Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone.
[ Stability ] Stable at normal temperatures and pressures.
[ Usage ] A progesterone receptor antagonist with partial agonist activity. Abortifacient.
