Description
Synonym: Madecassol
CAS Number: 16830-15-2
Purity: ≥98%
Molecular Weight: 959.12
Molecular Formula: C48H78O19
Specification: 20mg
Appearance: White powder
Physical State: Solid
Storage: Desiccate at room temperature
Melting Point: 230 – 233 ºC
Application: Is used to study potential treatments for wounds and burns
Description:
Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat a variety of ailments including dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. In various wound healing models, topical application (0.2-0.4%), injection (1 mg), or ingestion (1 mg/kg) of asiaticoside has been shown to increase hydroxyproline content, improve tensile strength, increase collagen synthesis and remodeling of the collagen matrix, promote epithelialization, stimulate glycosaminoglycan synthesis, and elevate antioxidant levels.
Asiaticoside is a terpenoid component extracted form Centella asiatica. It has been demonstrated to increase collagen synthesis and therefore anti-wrinkle activity. Skin ageing appears to be principally related to a decrease in the levels of type I collagen, the primary component of the skin dermis. Type I collagen is also known to impart tensile strength to skin. In vitro evaluations have demonstrated the receptorial activity of Asiaticoside on collagen synthesis. Clinical evaluations confirm its anti-wrinkle efficacy.
