Description
[ Synonyms ] Pseudomonic acid; Bactroban; Mupirocine; Mupirocinum
[ CAS NO. ] 12650-69-0
[ Molecular Formula ] C26H44O9
[ Molecular weight ] 500.629
[ Appearance ] White or almost white powder
[ Application ]
Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle, impetigo, open wounds, etc. It is also useful in the treatment of superficial methicillin-resistant Staphylococcus aureus (MRSA) infections. Mupirocin is inactive for most anaerobic bacteria, mycobacteria, mycoplasma, chlamydia, yeast and fungi.
COA of Mupirocin
Identification: Infrared absorption spectrophotometry
Melting point: 78℃
PH: 3.78
Specific optical rotation: – 20
Water: 0.26%
Ethyl Acetate Residual: 2880.2ppm
Heptane Residual: 1067.4ppm
Acetone Residual: 10.6ppm
Assay: 934.0ug/mg
About Mupirocin
Mupirocin is a topical antibiotic useful against superficial skin infections such as impetigo or folliculitis. It may also be used to get rid of methicillin-resistant S. aureus (MRSA) when present in the nose without symptoms. Due to concerns of developing resistance, use for greater than ten days is not recommended. It is used as a cream or ointment applied to the skin.
Common side effects include itchiness and rash at the site of application, headache, and nausea. Long term use may result in increased growth of fungi. Use during pregnancy and breastfeeding appears to be safe. Mupirocin is in the carboxylic acid class of medications. It works by blocking a bacteria’s ability to make protein, which usually results in bacterial death.
[ Storage ] Protected from light
