Description
CAS : 9001-48-3
EC number : EC 1.8.1.7
Product Description：
Glutathione reductase, also known as GSR or GR, is an enzyme (EC 1.8.1.7) which reduces glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant.
For every mole of oxidized glutathione (GSSG) one mole of NADPH is required to reduce GSSG to GSH. The enzyme forms a FAD bound homodimer. The glutathione reductase is conserved between all kingdoms. In bacteria, yeasts and animals one glutathione reductase gene is found, however in plant genomes two GR genes are encoded. Drosophila and Trypanosomes do not have any GR at all . In these organisms glutathione reduction is performed by either the thioredoxin, or the trypanothione system, respectively.
